原著論文

Kameda H, Yamaoka K, Yamanishi Y, Tada M, Koike R, Nakajima A, Fusama M, Fujii T.
Japan College of Rheumatology guidance for the use of methotrexate in patients with rheumatoid arthritis: Secondary publication.
Mod Rheumatol 34:1-10, 2023
Tanaka Y, Okuda K, Takeuchi Y, Katayama K, Haji Y, Yamanishi Y, Tribanek M, Guimbal-Schmolck C, Takeuchi T.
Efficacy and tolerability of subcutaneously administered methotrexate including dose escalation in long-term treatment of rheumatoid arthritis in a Japanese population.

Mod Rheumatol 33:680-689, 2023

Atsumi T, Yamamoto K, Takeuchi T, Yamanaka H, Ishiguro N, Tanaka Y, Eguchi K, Watanabe A, Origasa H, Yasuda S, Yamanishi Y, Kita Y, Matsubara T, Iwamoto M, Shoji T, Okada T, van der Heijde D, Miyasaka N, Koike T.

The first double-blind, randomised, parallel-group certolizumab pegol study in methotrexate-naive early rheumatoid arthritis patients with poor prognostic factors, C-OPERA, shows inhibition of radiographic progression.
Ann Rheum Dis 75: 75-83, 2016
Atsumi T, Tanaka Y, Yamamoto K, Takeuchi T, Yamanaka H, Ishiguro N, Eguchi K, Watanabe A, Origasa H, Yasuda S, Yamanishi Y, Kita Y, Matsubara T, Iwamoto M, Shoji T, Togo O, Okada T, van der Heijde D, Miyasaka N, Koike T.
Clinical benefit of 1-year certolizumab pegol (CZP) add-on therapy to methotrexate treatment in patients with early rheumatoid arthritis was observed following CZP discontinuation: 2-year results of the C-OPERA study, a phase III randomised trial.
Ann Rheum Dis 76: 1348-1356, 2017
Yamanishi Y, Boyle DL, Green DR, Keystone EC, Connor A, Zollman S, Firestein GS.
p53 tumor suppressor gene mutations in fibroblast-like synoviocytes from erosion synovium and non-erosion synovium in rheumatoid arthritis.
Arthritis Res Ther 7:R12-R18, 2005
Cramer T, Yamanishi Y, Clausen BE, Forster I, Pawlinski R, Mackman N, Haase VH, Jaenisch R, Corr M, Nizet V, Firestein GS, Gerber HP, Ferrara N, Johnson RS.
HIF-1α is essential for myeloid cell-mediated inflammation.
Cell, 112:645-57, 2003
Yamanishi Y, Boyle DL, Rosengren S, Green DR, Zvaifler NJ, Firestein GS.
Regional analysis of p53 mutations in rheumatoid arthritis synovium.
Proc Natl Acad Sci USA 99: 10025-30, 2002
Han Z, Chang L, Yamanishi Y, Karin M, Firestein GS.
Joint damage and inflammation in c-Jun N-terminal kinase 2 knockout mice with passive murine collagen-induced arthritis.
Arthritis Rheum 46:818-23, 2002
Yamanishi Y, Boyle DL, Clark M, Maki RA, Tortorella MD, Arner EC, Firestein GS.
Expression and regulation of aggrecanase in arthritis: the role of TGF-beta.
J Immunol 168:1405-12, 2002
Yamanishi Y, Boyle DL, Pinkoski MJ, Mahboubi A, Lin T, Han Z, Zvaifler NJ, Green DR, Firestein GS. Regulation of Joint Destruction and Inflammation by p53 in Collagen-Induced Arthritis.
Am J Pathol 160:123-30, 2002
Aupperle KR, Yamanishi Y, Bennett BL, Mercurio F, Boyle DL, Firestein GS.
Expression and regulation of inducible IkappaB kinase (IKK-i) in human fibroblast-like synoviocytes.
Cell Immunol 214:54-9, 2001
Yamanishi Y, Hiyama K, Ishioka S, Maeda H, Yamanaka T, Kurose Y, Yamakido M.
Telomerase activity in the synovial tissues of chronic inflammatory and non-inflammatory rheumatic diseases.
Int J Mol Med 4: 513-7, 1999
Yamanishi Y, Hiyama K, Maeda H, Ishioka S, Murakami T, Hiyama E, Kurose Y, Shay JW, Yamakido M.
Telomerase activity in rheumatoid synovium correlates with the mononuclear cell infiltration level and disease aggressiveness of rheumatoid arthritis.
J Rheumatol 25: 214-20, 1998
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